Male Hormone Panel: Patient Overview
What You Can Do About Male Hormone Imbalance
Optimal health is dependent on a balance of hormones, not just a single hormone. Currently, men with low androgen
hormones can benefit from hormone replacement therapy. Men with imbalances in their levels of androgen to estrogen and
progesterone can also benefit from hormone supplements.
Supplemental hormones can be given by mouth, injection, skin patch or implant. Androgen supplementation, in states of
deficit, improves alertness and produces a feeling of well-being, with a reduction in abdominal fat and enhanced lean body
Testosterone production in males is mainly a testicular function. The pituitary sex hormones luteinizing hormone (LH) and
follicle-stimulating hormone (FSH) stimulate and regulate this function. Specifically, LH stimulates testosterone production
in the testicles. This process is under negative feedback, meaning that testosterone levels regulate LH secretion. FSH and
testosterone stimulate sperm production.
Why Measure Male Hormones?
Measurements of hormones can be used in two general ways:
• To estimate the body’s own production as a baseline test.
• To measure levels of hormones after supplementation in therapeutic monitoring.
Baseline measurements show normal and abnormal levels of six distinct hormones, shown in the boxes in Diagram 1. If
the levels are too low, too high or hormone ratios are outside of expected limits, an objective treatment plan can
be developed for the patient. Symptoms are not a substitute for measuring hormone levels, because many symptoms may
involve non-hormonal factors.
Using appropriate tests for monitoring hormone therapy is crucial in establishing the appropriate dosing regimen. This
reduces the chance of undesirable side effects and maximizes beneficial effects. For example, excessive use of androgens
(testosterone, androstenedione, DHEA and testosterone derivatives) can activate subclinical prostatic tumors which are
androgen-dependent. Monitoring is especially important in older males. By the age of 70, at least 50% of men have subclinical
prostate cancer. These individuals are especially susceptible to growth stimulation by androgens.
The roles of the seven tested hormones are highlighted in the following descriptions of each:
DHEA - Is the precursor for both male and female hormones— and anti-stress hormone produced by the
adrenal glands. Unmonitored intake can easily alter the delicate balance between male and female hormones.
Androstenedione - Is a weak (androgen) and a precursor to both male and female hormones. Unmonitored
intake in men can cause excessive female hormone production with minimal male hormone production. In women, unmonitored
intake usually causes excess male hormone production with body and facial hair stimulation.
Testosterone - Is the main testicular androgen and is a precursor to the highly potent
dihydrotestosterone male hormone. Excessive amounts of testosterone promote hardening of the blood vessels, aggression,
prostate problems and an increase in total cholesterol.
Dihydrotestosterone (DHT) - Is made from testosterone in certain tissues. The rate of its production
is controlled by the level of free active progesterone. Excess DHT causes prostate enlargement and thinning of scalp hair.
Progesterone - Is a hormone important to both men and women. It is a natural calming agent to our nervous
system. It also keeps in check excessive DHT production and counterbalances the effects of excessive estrone. Unmonitored
intake can lead to breast enlargement, depression and weight gain.
Estrone - Is an estrogen that both men and women produce in the fat cells. The more fat, the more
estrone, which in turn promotes fat deposits. It is produced from androstenedione, and excess of estrone can cause breast
enlargement and contribute to prostate enlargement. In males, a certain low level of estrone is mandatory to balance the
Estradiol - Is another estrogen that is much more powerful than estrone. It is partially formed in the
testes but mostly in the perepheral tissues from both the testicular and adrenal androgens.
What We Test and What It Tells You
Using a saliva sample, the regular MHP panel measures seven hormones: DHEA, androstenedione, testosterone,
dihydrotestosterone, estrone, estradiol and progesterone. The expanded panel measures these seven hormones plus
FSH and LH. The hormone levels in saliva reflect the active tissue concentrations, while blood contains mostly
protein- bound hormones, whose active levels can only be estimated at best. Urine contains both the active hormones
and numerous metabolites and can only provide a gross estimate of hormone production over time. Active fraction
measurements from saliva are superior to blood and urine for use in diagnosis and treatment.
This Test is For You if You Are:
Middle-aged and experiencing any of these conditions:
Young and experiencing any of these conditions:
- Impaired libido
- Erectile dysfunction
- Baldness and/or extremity hair thinning
- Fat accumulation around the waist
- Urinary problems such as pain, frequency or urgency— or interrupted stream
- Changes in sleeping habits
- Lack of enthusiasm for life
- Increase in bad cholesterol—decrease in good cholesterol
- Impaired libido
- Erectile dysfunction
- Early baldness
- Inability to lose weight
How Do You Benefit?
There are five distinct ways that you can benefit from using the saliva tests in the Male Hormone Panel:
- They are affordable and less expensive than blood or urine tests. You save $250 - $300 on seven hormones.
- The collection procedure spares you from the biohazards and pain of venipunctures.
- Results are more clinically reflective of your hormone status and needs.
- Results can lead to an individualized and customized treatment plan using natural hormones.
- You will minimize overdosing and underdosing. This will ensure that you use only the proper hormones in the appropriate
amounts. With salivary hormone testing, guesswork is minimized.
Use the Male Hormone Panel to help restore well-being, vitality and passion for life.
Taking hormones without an evaluation of the actual need for specific hormones entails risks that are both serious
With two additional tests for LH and FSH, our expanded Male Hormone Panel can accurately identify the origin of
the most common male hormone problems.