The prevalence of food allergy, sensitivity, and related complaints in the general population is significant. Many food sensitivities are clinically silent, but their long-term effects may be serious.

In addition to chronic intestinal inflammation and malabsorption, systemic associations with food allergies and sensitivities include thyroid disease, type 1 diabetes, neurologic disorders, and increased risk of cancer.


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Food Panel: Provider Overview

Adverse Food Reactions

Adverse food reactions may occur due to a variety of reasons. In general, these reactions are subdivided into immune and non-immune reactions. Examples of non-immune type food reactions include:
  • Enzyme deficiencies (e.g. lactose intolerance)
  • Structural abnormalities (e.g. pyloric stenosis)
  • Other conditions (e.g. gallbladder disease, pancreatitis)
Immune-based reactions to food, or food allergies, can be classified as IgE-mediated (classic allergy) and non or mixed IgE-mediated immune reactions. Non IgE-mediated food reactions are commonly referred to as food sensitivities.

Symptoms of food allergy and sensitivity may not be exclusive to the gastrointestinal system and may involve:
  • Skin: hives, dermatitis, eczema
  • Musculoskeletal: joint pain and inflammation
  • Respiratory: sinusitis, asthma, Heiner syndrome
  • Neurologic: headache, migraine, insomnia, irritability, anxiety, depression
  • Immune: decreased immune function
  • Hematologic: anemia, blood clotting abnormalities
  • General: fatigue, weight loss
If left untreated, food allergies and sensitivities can progress to more severe pathologies (such as celiac disease) in which the intestinal mucosa is damaged, potentially resulting in chronic malabsorption and inflammation.

Other conditions associated with untreated food allergies include:
  • Autoimmune Disease: Liver and bile duct disorders, type I diabetes, systemic lupus erythematosus (SLE)
  • Cancer: Lymphoma, gastrointestinal cancer
  • Thyroid Conditions: Hypothyroidism, hyperthyroidism
  • Decreased Bone Mineral Density: Osteopenia, osteoporosis
  • Reproductive System Dysfunction: Impotence, infertility (males and females), menstrual irregularities
  • Neurological and Psychiatric Disorders: Migraines, insomnia, anxiety, depression, postural imbalance, nerve tingling, numbness

Tests Included in the Food Panel:

The Food Panel (FP) measures antibodies (salivary IgA or sIgA) to some of the most common food allergens – gluten (gliadin), milk (casein), egg (ovalbumin), and soy (protein). It also includes a measurement of the total salivary sIgA to provide context for interpreting the food specific sIgA results.
  • Milk (casein) antibody, sIgA
  • Soy (protein) antibody, sIgA
  • Egg (ovalbumin) antibody, sIgA
  • Gluten (gliadin) antibody, sIgA
  • Total salivary sIgA
The Diagnos-Techs Food Panel (FP) allows for identification of specific food sensitivities, which can help guide appropriate treatment through diet.